Tangential: Whenever I see a reference to cerebrospinal fluid, I can’t help but think of these and shiver a little -

http://www.fox10phoenix.com/story/22136887/2013/05/01/mans-runny-nose-was-actually-brain-fluid-leaking

http://abcnews.go.com/Health/arizona-woman-dies-brain-fluid-leaks-nose/story?id=17849038&singlePage=true